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Restored Republic via a GCR as of Nov. 19, 2018

Restored Republic via a GCR: Update as of Nov. 19, 2018 Compiled 19 Nov. 12:01 am EST by Judy Byington, MSW, LCSW, ret. CEO, Child Abuse R...

Sunday, June 24, 2018

Kratom -- Alternative for Opium Withdrawal

Kratom as an Alternative for Opium Withdrawal

June 24, 2018

Story at-a-glance

Opioid overdose is the No. 1 cause of death of Americans under the age of 50, and opioid addiction is so widespread it has led to a decline in the average life expectancy in the U.S.

Kratom has been used as a traditional medicine in Thailand and Malaysia for centuries, primarily to boost energy. It also has a long history of use as an opium substitute and to wean off opium

Kratom contains corynantheine alkaloids such as mitragynine, which interacts with opioid receptors, adrenergic receptors, serotonin receptors, dopamine receptors and adenosine receptors

While the alkaloids in kratom bind to opioid receptors, animal trials suggest the abuse potential of kratom is very low

A compound found in dried kratom leaves, 7-hydroxymitragynine is known to be a fast-acting full opioid agonist that substitutes directly for morphine and can be habit forming. This compound does not appear to be present in detectable amounts in fresh extracts, so using tea from fresh leaves and/or extracts may be a way to circumvent its addiction potential

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